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Question 1
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The axons of which neurons serve as the only output from the cerebellar cortex?
Your Answer: Purkinje
Explanation:The cerebellar cortex consist of 3 layers. The molecular layer, the granule cell layer and the Purkinje cell layer in the middle. The Purkinje cells project into the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex.
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This question is part of the following fields:
- Neuro-anatomy
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Question 2
Incorrect
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Endolymph in the inner ear is rich in:
Your Answer: Chloride
Correct Answer: K
Explanation:Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.
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This question is part of the following fields:
- Neuro-anatomy
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Question 3
Correct
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Which part of the cerebellum is primarily responsible for interacting with the motor cortex and planning and programming movements?
Your Answer: Cerebrocerebellum
Explanation:The cerebrocerebellum is the largest functional subdivision of the cerebellum, comprising of the lateral hemispheres and the dentate nuclei. It is involved in the planning and timing of movements, and in the cognitive functions of the cerebellum.
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This question is part of the following fields:
- Neuro-anatomy
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Question 4
Incorrect
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Which of the following tracts are involved in the control of vital functions?
Your Answer: Rubrospinal
Correct Answer: Reticulospinal
Explanation:Reticulospinal tract pass down from the reticular formation of the mid brain, pons and medulla. It descends in the lateral white column. Both sets of fibers enter the anterior grey column and may facilitate or inhibit the gamma and alpha neurons. By this means the reticulospinal tract controls voluntary and reflex activities. It also contains the descending autonomic fiber, thus providing a pathway for the hypothalamus to control the sympathetic and parasympathetic pathways.
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This question is part of the following fields:
- Neuro-anatomy
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Question 5
Correct
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Question 6
Correct
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The primary auditory cortex is:
Your Answer: Brodmann area 41
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
Primary Sensory 3,1,2
Primary Motor 4
Premotor 6
Primary Visual 17
Primary Auditory 41
Brocas 44 -
This question is part of the following fields:
- Neuro-anatomy
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Question 7
Correct
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Where are the cell bodies to the preganglionic neurons located?
Your Answer: Midbrain
Explanation:The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves. These cranial nerves take origin from the midbrain.
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This question is part of the following fields:
- Neuro-anatomy
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Question 8
Correct
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Salty taste is triggered by:
Your Answer: Amiloride-sensitive sodium channel
Explanation:Amiloride-sensitive sodium channels also known as epithelial Na channels is a membrane bound ion channel that is selectively permeable to Na+ ions. These channels are located throughout different epithelial membranes in the body. It is found in taste receptor cells, where it plays an important role in salt taste perception. They are also located in the kidney, the lung and the colon. Hyperpolarization-activated, cyclic nucleotide-gated (HCN) voltage-gated ion channels are widely seen in the cortex, hippocampus, thalamus and brain regions that underlie the generation of both focal and generalized-onset seizures. The metabotropic glutamate receptor (mGluRs) perform a variety of functions in the central and peripheral nervous systems. They are involved in learning, memory, anxiety, and the perception of pain. Gustducin is a G protein associated with taste and gustatory system. It plays a major role in sensation of bitter, sweet and umami stimuli.
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This question is part of the following fields:
- Neuro-anatomy
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Question 9
Correct
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Question 10
Incorrect
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The cerebellum consist of which three lobes?
Your Answer: Anterior, posterior and inferior
Correct Answer: Anterior, posterior and flocculonodular
Explanation:The cerebellum consists of 3 lobes; Anterior, Posterior and Flocculonodular lobe.
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This question is part of the following fields:
- Neuro-anatomy
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Question 11
Correct
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Question 12
Incorrect
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The hippocampus is involved in the memory of:
Your Answer: Classical conditioning
Correct Answer: Facts
Explanation:The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.
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This question is part of the following fields:
- Neuro-anatomy
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Question 13
Correct
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The main reason for the prolonged effect of the withdrawal reflex is:
Your Answer: Multiple connections between afferent and efferent neurons
Explanation:The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.
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This question is part of the following fields:
- Neuro-anatomy
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Question 14
Incorrect
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Question 15
Correct
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The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?
Your Answer: Ia
Explanation:Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.
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This question is part of the following fields:
- Neuro-anatomy
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Question 16
Incorrect
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The layers of the neocortex from the 1st to the 6th are arranged as follows:
Your Answer: Internal granular, internal pyramidal, multiform, molecular, external granular, external pyramidal
Correct Answer: Molecular, external granular, external pyramidal, internal granular, internal pyramidal, multiform
Explanation:The layers of neocortex from outermost to innermost include: the molecular, external granular layer, external pyramidal, internal granular, internal pyramidal and multiform layer.
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This question is part of the following fields:
- Neuro-anatomy
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Question 17
Correct
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The inverse stretch reflex causing muscle relaxation when excessive force is applied to a muscle is mediated by which sensory organ?
Your Answer: Golgi tendon organ
Explanation:Both the muscle spindle and Golgi tendon body are proprioceptors. The Golgi tendon reflex is a normal component of the reflex arc of the peripheral nervous system. In a Golgi tendon reflex, skeletal muscle contraction causes the antagonist muscle to simultaneously lengthen and relax. This reflex is also called the inverse myotatic reflex, because it is the inverse of the stretch reflex.
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This question is part of the following fields:
- Neuro-anatomy
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Question 18
Correct
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Which of the following is the smallest cell of the nervous system?
Your Answer: Microglia
Explanation:Microglia are the smallest of the neuroglial cells in the nervous system. They are scattered throughout the central nervous system and have phagocytic properties.
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This question is part of the following fields:
- Neuro-anatomy
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Question 19
Correct
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The neurotransmitter utilised by the Purkinje cells is:
Your Answer: GABA
Explanation:The cerebellar cortex consist of 3 layers: the molecular layer, the granular cell layer and the Purkinje cell layer. Purkinje cells play a fundamental role in controlling motor movement. They release a neurotransmitter called GABA (gamma-aminobutyric acid) which exerts inhibitory actions thereby reducing transmission of impulses. These inhibitory functions enable purkinje cells to regulate and coordinate motor movements.
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This question is part of the following fields:
- Neuro-anatomy
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Question 20
Incorrect
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Which serotonergic receptor is associated with vomiting?
Your Answer: 5ht2a
Correct Answer: 5ht3
Explanation:5ht3 is a receptor strongly associated with vomiting, present in vagal afferents, the solitary tract nucleus (STN), and the area posterior. For this reason, 5ht3 antagonists are commonly used as antiemetic drugs. They include ondansetron, tropisetron, and granisetron.
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This question is part of the following fields:
- Neuro-anatomy
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Question 21
Incorrect
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Sequence of events in formation of speech are:
Your Answer: Insula---Wernicke's area---arcuate fasciculus---broca’s area---motor cortex ---speech
Correct Answer: Wernicke’s area---arcuate fasciculus---broca’s area---insula---motor cortex---speech
Explanation:Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language. Firstly, the language is accessed in the Wernicke’s area and these words are sent via the arcuate fasciculus to the Broca’s area, where instructions for articulation is generated. This is then sent from Broca’s are to the motor cortex for the articulation.
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This question is part of the following fields:
- Neuro-anatomy
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Question 22
Correct
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The spinal cord receive its blood supply from the following arteries except:
Your Answer: Lateral spinal artery
Explanation:The spinal cord (SC) is supplied by the single anterior spinal artery which supplies the anterior two thirds of the SC and paired posterior spinal arteries supplying the posterior one third. Anastomoses between the spinal arteries supply the lateral column. These arteries originate near the cervico-occipital junction and therefore have a smaller calibre and often discontinue. Thus, they require reinforcement by segmental/radicular arteries which are branches of the ascending cervical artery, deep cervical artery, intercostal arteries, lumbar arteries and lateral sacral arteries
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This question is part of the following fields:
- Neuro-anatomy
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Question 23
Incorrect
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The motor speech area (Brocas Area) is:
Your Answer: Brodmann area 6
Correct Answer: Brodmann area 44
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
Primary Sensory 3,1,2
Primary Motor 4
Premotor 6
Primary Visual 17
Primary Auditory 41
Brocas 44 -
This question is part of the following fields:
- Neuro-anatomy
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Question 24
Incorrect
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The outer and inner surfaces of the arachnoid mater is covered with:
Your Answer: Columnar epithelial cells
Correct Answer: Mesothelial cells
Explanation:The arachnoid mater is one of the three meninges that covers the brain and spinal cord. It is interposed between the two other meninges, the more superficial and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The arachnoid mater consists of a subdural mesothelial layer and a compact central layer
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This question is part of the following fields:
- Neuro-anatomy
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Question 25
Correct
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Question 26
Correct
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The thalamus is a large collection of neuronal groups within the diencephalons which participates in:
Your Answer: Sensory, motor and limbic
Explanation:The thalamus has multiple functions. It is the relay station for every sensory system (except olfactory, regulates the sleep-wake cycle and consciousness and also relays motor information.
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This question is part of the following fields:
- Neuro-anatomy
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Question 27
Correct
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Which of the following do not pass through the cavernous sinus?
Your Answer: CN 2
Explanation:Oculomotor nerve (N3), trochlear nerve (N4), ophthalmic and mandibular divisions of the trigeminal nerve (N5) pass along its lateral border. The abducent nerve (N6) passes through it along with the internal carotid artery.
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This question is part of the following fields:
- Neuro-anatomy
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Question 28
Correct
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Question 29
Correct
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Which of the following is not innervated by the parasympathetic nerve supply?
Your Answer: Radial muscle of iris
Explanation:The sphincter pupillae is supplied by the parasympathetic fibers from the Edinger Westphal nucleus of the oculomotor nerve. The dilator pupillae (radial muscle) is supplied by the postganglionic fibers of the superior cervical sympathetic ganglion. The parasympathetic nerve supply to the salivary glands originate in the parasympathetic nucleus of the facial nerve (superior salivatory nucleus) and the glossopharyngeal nerve (inferior salivatory nucleus). The parasympathetic preganglionic fibers originate in the dorsal nucleus of the vagus nerve and descend into the thorax in the vagus nerve. The fibers terminate by synapsing with postganglionic neurons in the cardiac plexuses. Postganglionic fibers terminate on the sinoatrial and atrioventricular nodes and on the coronary arteries Parasympathetic supply to the stomach is via the vagus nerve.
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This question is part of the following fields:
- Neuro-anatomy
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Question 30
Incorrect
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Regarding taste threshold and intensity discrimination:
Your Answer: 10% change in concentration of substance tasted is necessary before an intensity difference can be detected
Correct Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected
Explanation:The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.
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This question is part of the following fields:
- Neuro-anatomy
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