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  • Question 1 - The oesophagus is lined by ...

    Incorrect

    • The oesophagus is lined by

      Your Answer: Simple columnar epithelium

      Correct Answer: Stratified squamous epithelium

      Explanation:

      The wall of the oesophagus from the lumen outwards consists of mucosa, submucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. The mucosa is a stratified squamous epithelium of around three layers of squamous cells, which contrasts to the single layer of columnar cells of the stomach. The transition between these two types of epithelium is visible as a zig-zag line. Most of the muscle is smooth muscle although striated muscle predominates in its upper two thirds.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.1
      Seconds
  • Question 2 - Carbohydrates digestion starts in the ...

    Incorrect

    • Carbohydrates digestion starts in the

      Your Answer: Pancreas

      Correct Answer: Mouth

      Explanation:

      Digestion begins in the mouth with the secretion of saliva and its digestive enzymes. Food is formed into a bolus by the mechanical mastication and swallowed into the oesophagus from where it enters the stomach through the action of peristalsis.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.1
      Seconds
  • Question 3 - The principal enzyme of lipid digestion is: ...

    Correct

    • The principal enzyme of lipid digestion is:

      Your Answer: Lipase

      Explanation:

      Lipase is the principle enzyme that digest lipids. Amylase digest carbohydrates. Colipase is a co-enzyme that optimize the activity of lipase. Trypsin digest proteins and cholesterol esterase digest cholesterol.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      6.2
      Seconds
  • Question 4 - Majority of gastrinomas are found in the: ...

    Incorrect

    • Majority of gastrinomas are found in the:

      Your Answer: Pancreas

      Correct Answer: Duodenum

      Explanation:

      A gastrinoma is a tumour in the pancreas or duodenum that secretes excess of gastrin leading to ulceration in the duodenum, stomach and the small intestine. It is usually found in the duodenum, although it may arise in the stomach or pancreas. Those occurring in the pancreas have a greater potential for malignancy. Most gastrinomas are found in the gastrinoma triangle; this is bound by the junction of cystic and common bile ducts, junction of the second and third parts of the duodenum, and the junction of the neck and body of the pancreas.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      5.6
      Seconds
  • Question 5 - Which hormone results in the production of pancreatic juice rich in enzymes but...

    Incorrect

    • Which hormone results in the production of pancreatic juice rich in enzymes but low in volume?

      Your Answer: Somatostatin

      Correct Answer: Cholecystokinin

      Explanation:

      Cholecystokinin (CCK) mediates digestion in the small intestine by inhibiting gastric emptying and decreasing gastric acid secretion. It stimulates the acinar cells of the pancreas to release a juice rich in pancreatic digestive enzymes, hence the old name pancreozymin.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.5
      Seconds
  • Question 6 - The alpha amylases hydrolyse which linkages in the ingested polysaccharides? ...

    Incorrect

    • The alpha amylases hydrolyse which linkages in the ingested polysaccharides?

      Your Answer: 1:6α linkages

      Correct Answer: 1:4α linkages

      Explanation:

      Alfa amylase hydrolyses the α (1-4) glyosidic bonds in amylose and amylopectin and leave primarily maltose.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.5
      Seconds
  • Question 7 - The haustral pattern seen in the normal colon is produced by ...

    Incorrect

    • The haustral pattern seen in the normal colon is produced by

      Your Answer: Plica circularis

      Correct Answer: Taenia coli

      Explanation:

      The haustra (singular haustrum) of the colon are the small pouches caused by sacculation (sac formation), which give the colon its segmented appearance. The teniae coli run the length of the large intestine. Because the taeniae coli are shorter than the intestine, the colon becomes sacculated between the taeniae coli, forming the haustra.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.9
      Seconds
  • Question 8 - The pressure in the portal circulation is normally adjusted in the: ...

    Incorrect

    • The pressure in the portal circulation is normally adjusted in the:

      Your Answer: Portal veins

      Correct Answer: Sinusoids

      Explanation:

      The pressure in the portal circulation depends on the pressure of the hepatic sinusoids mainly because the direction of transport of nutrients in the portal vein occurs from the portal vein to the hepatic sinusoids.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      8.3
      Seconds
  • Question 9 - Pepsinogens are inactive pepsin precursors which are activated by ...

    Incorrect

    • Pepsinogens are inactive pepsin precursors which are activated by

      Your Answer: Saliva

      Correct Answer: Gastric acid

      Explanation:

      Pepsinogen is converted to pepsin by the action of hydrochloric acid i.e. gastric acid

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      6.5
      Seconds
  • Question 10 - Which of the following is NOT a pancreatic enzyme? ...

    Incorrect

    • Which of the following is NOT a pancreatic enzyme?

      Your Answer: Amylase

      Correct Answer: Pepsinogen 1

      Explanation:

      Pancreatic juice, composed of the secretions of both ductal and acinar cells, is made up of the following digestive enzymes:Trypsinogen, which is an inactive(zymogenic) protease that, once activated in the duodenum into trypsin, breaks down proteins at the basic amino acids. Trypsinogen is activated via the duodenal enzyme enterokinase into its active form trypsin.Colipase is a protein co-enzyme required for optimal enzyme activity of pancreatic lipase. It is secreted by the pancreas in an inactive form, procolipase, which is activated in the intestinal lumen by trypsin.Chymotrypsinogen, which is an inactive (zymogenic) protease that, once activated by duodenal enterokinase, breaks down proteins at their aromatic amino acids. Chymotrypsinogen can also be activated by trypsin.Carboxypeptidase, which is a protease that takes off the terminal amino acid group from a proteinSeveral elastases that degrade the protein elastin and some other proteins.Pancreatic lipase that degrades triglycerides into fatty acids and glycerol.Sterol esterasePhospholipaseSeveral nucleases that degrade nucleic acids, like DNase and RNase.Pancreatic amylase that breaks down starch and glycogen which are alpha-linked glucose polymers.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.2
      Seconds
  • Question 11 - Which glucose transporter is responsible for the uptake of dietary glucose from the...

    Incorrect

    • Which glucose transporter is responsible for the uptake of dietary glucose from the gut?

      Your Answer: SGLT2

      Correct Answer: SGLT1

      Explanation:

      SGLT 1 is responsible for the uptake of glucose via secondary active transport from the small intestine and the renal tubules.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      5.5
      Seconds
  • Question 12 - A patient with a VIPoma (VIP secreting tumour) is likely to exhibit which...

    Incorrect

    • A patient with a VIPoma (VIP secreting tumour) is likely to exhibit which of the following?

      Your Answer: Duodenal ulceration

      Correct Answer: Severe diarrhoea

      Explanation:

      Vasoactive inhibitory peptide (VIP) is found in the nerves innervating the GIT. It markedly stimulates the secretion of intestinal electrolytes and also with them water. This results in secretary diarrhoea. Along with that it also relaxes intestinal smooth muscle including the sphincters, it also results in dilation of the peripheral blood vessels and along with this its also inhibits gastric acid secretions. A VIPoma will exaggerate all this.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      15.4
      Seconds
  • Question 13 - Regarding short-chain fatty acids, all the following are true except: ...

    Incorrect

    • Regarding short-chain fatty acids, all the following are true except:

      Your Answer: They are two-to five-carbon weak acids

      Correct Answer: They are produced in the small intestine but their absorption occurs in the colon

      Explanation:

      Short chain fatty acids (SCFAs) have carbon chains of 2-5 carbon atoms. They are produced in the large intestine and are also absorbed there. They exert a trophic effect on the colonic epithelial layer in absorption of sodium. In the absence of short chain fatty acids there is a loss of sodium and water. Transport of SCFA is coupled with sodium thus absorption leads to the accumulation in the lumen of HCO3, a rise in pH, fall in pCO2 and stimulation of Na+ and water transport. The effect on Na+ transport is thought to indicate the presence of a Na+/H+ exchange in the cell membrane.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      8.6
      Seconds
  • Question 14 - Regarding the anatomy of the intestine, the muscularis propria contains all of which...

    Correct

    • Regarding the anatomy of the intestine, the muscularis propria contains all of which of the following constituents?

      Your Answer: Circular muscle, myenteric plexus, longitudinal muscle

      Explanation:

      The muscularis mucosa/propria consists of the inner circular muscles and the outer longitudinal muscles. Between these muscles is the myenteric plexus.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      6.4
      Seconds
  • Question 15 - The parasympathetic innervation of the parotid salivary gland arrives from the salivary nuclei:...

    Incorrect

    • The parasympathetic innervation of the parotid salivary gland arrives from the salivary nuclei:

      Your Answer: CN X

      Correct Answer: CN IX

      Explanation:

      Parasympathetic presynaptic nerve fibers from the glossopharyngeal nerve (CN IX) synapse in the otic ganglion and the postsynaptic parasympathetic nerve fibers pass to the parotid gland via the auriculotemporal nerve.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      9.8
      Seconds
  • Question 16 - A patient with achalasia ...

    Correct

    • A patient with achalasia

      Your Answer: Has decreased production of vasoactive intestinal polypeptide (VIP)

      Explanation:

      Oesophageal achalasia is an oesophageal motility disorder involving the smooth muscle layer of the oesophagus and the lower oesophageal sphincter (LES). It is characterized by incomplete LES relaxation, increased LES tone, and lack of peristalsis of the oesophagus (inability of smooth muscle to move food down the oesophagus) in the absence of other explanations like cancer or fibrosis. In achalasia, there is loss of nitric oxide (NO) and vasoactive intestinal polypeptide (VIP) releasing inhibitory neurons.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      9.6
      Seconds
  • Question 17 - Intrinsic Factor is released by, ...

    Correct

    • Intrinsic Factor is released by,

      Your Answer: Parietal cell

      Explanation:

      Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.5
      Seconds
  • Question 18 - Which of the following is true with regard to the acini? ...

    Incorrect

    • Which of the following is true with regard to the acini?

      Your Answer: Peripheral zone is least oxygenated

      Correct Answer: The central zone (Zone III) is the least oxygenated

      Explanation:

      The acini are divided into zone I (periportal), zone II (transition zone), and zone III (pericentral). Cells located close to the portal triad or peripheral zone which consist of an arteriole from the hepatic artery are the most oxygenated cells. Cells in the central zone (III) are least oxygenated and mainly receive blood supply from the central vein which is a branch of hepatic vein.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.8
      Seconds
  • Question 19 - Which of the following factors is not completely produced in the liver? ...

    Incorrect

    • Which of the following factors is not completely produced in the liver?

      Your Answer: Factor vii

      Correct Answer: Factor viii

      Explanation:

      Factor VIII is produced in liver sinusoidal cells and endothelial cells outside of the liver throughout the body. This protein circulates in the bloodstream in an inactive form, bound to another molecule called von Willebrand factor, until an injury that damages blood vessels occurs.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.5
      Seconds
  • Question 20 - Which enzyme is responsible for the formation of the active endopeptidases from their...

    Incorrect

    • Which enzyme is responsible for the formation of the active endopeptidases from their inactive precursors?

      Your Answer: Trypsin

      Correct Answer: Enterokinase

      Explanation:

      Enterokinase is a brush border enzyme of the duodenum that activates proteolytic enzymes for further digestion of proteins. Trypsinogen is converted to trypsin by the action of enterokinase. Trypsin and chymotrypsin are secreted by the pancreatic acinar cells and are enzymes that aid in protein digestion. Pepsin is secreted by chief cells of gastric mucosa. Procarboxydase is the inactive form of carboxypeptidase which is converted to its active form by trypsin and is secreted by pancreatic acinar cells.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.3
      Seconds
  • Question 21 - The parietal cells of the stomach secrete which of the following? ...

    Incorrect

    • The parietal cells of the stomach secrete which of the following?

      Your Answer: Mucus

      Correct Answer: Hydrochloric acid

      Explanation:

      Parietal cells are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and in the body of the stomach.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      8.6
      Seconds
  • Question 22 - Where in the course of the gastrointestinal tract does the first significant digestion...

    Incorrect

    • Where in the course of the gastrointestinal tract does the first significant digestion of fat begin in a normal human being?

      Your Answer: Stomach

      Correct Answer: Duodenum

      Explanation:

      The enzyme lipase which is responsible for digestion of fat is secreted by the exocrine pancreas in the 2nd part of the duodenum at the point where the pancreatic duct opens. It opens together with the common bile duct which contains bile that emulsify fat aiding in digestion. The oesophagus, stomach and mouth do not contain enzymes related to fat digestion.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.1
      Seconds
  • Question 23 - Which of the following acts on the pancreas to secrete pancreatic juice that...

    Incorrect

    • Which of the following acts on the pancreas to secrete pancreatic juice that is rich in enzymes?

      Your Answer: Chymotrypsin

      Correct Answer: CCK

      Explanation:

      CCK (Cholecystokinin): CCK is released by the duodenum in response to the presence of fats and proteins in the small intestine. It stimulates the pancreas to secrete enzyme-rich pancreatic juice, which aids in the digestion of fats, proteins, and carbohydrates. It also stimulates the gallbladder to contract and release bile.

      Secretin: Secretin is released by the duodenum in response to acidic chyme entering from the stomach. It primarily stimulates the pancreas to release bicarbonate-rich pancreatic juice to neutralize the acid, but it does not primarily stimulate enzyme secretion.

      Gastrin: Gastrin is produced by G-cells in the stomach. It stimulates gastric acid secretion by the stomach, not pancreatic enzyme secretion.

      Chymotrypsin: Chymotrypsin is an enzyme produced by the pancreas. It does not act to stimulate the pancreas; rather, it is a component of the pancreatic juice that helps digest proteins.

      Elastase: Elastase is also an enzyme produced by the pancreas. Like chymotrypsin, it is involved in the digestion of proteins and does not stimulate the pancreas.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      9.6
      Seconds
  • Question 24 - Vagotomy leads to the following: ...

    Incorrect

    • Vagotomy leads to the following:

      Your Answer: No peristalsis

      Correct Answer: Irregular and chaotic peristalsis

      Explanation:

      The Vagus nerve is primarily responsible for autonomic regulation involved in heart, lung and gastrointestinal function. The gastric branches supply the stomach. The right branch joins the celiac plexus and supplies the intestines. Vagotomy involves cutting of the vagus nerve or its branches which is a now-obsolete therapy that was performed for peptic ulcer disease. Vagotomy causes a decrease in peristalsis and a change in the emptying patterns of the stomach.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.3
      Seconds
  • Question 25 - Portal vein receives its blood from all the following except: ...

    Incorrect

    • Portal vein receives its blood from all the following except:

      Your Answer: Pancreas

      Correct Answer: Kidney

      Explanation:

      The portal vein receives blood from the intestines via the superior and inferior mesenteric veins, from stomach via the gastric veins and from the spleen and pancreas via splenic vein. The kidney is supplied by the renal artery and drains into the renal vein into the inferior venacava.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.4
      Seconds
  • Question 26 - Anti-gastroesophageal reflux mechanisms include the following except: ...

    Incorrect

    • Anti-gastroesophageal reflux mechanisms include the following except:

      Your Answer: The phrenoesophageal ligament

      Correct Answer: Peristaltic movements of the oesophagus

      Explanation:

      The lower oesophageal sphincter contracts preventing reflux of acid into the oesophagus. The sling muscles of the stomach, the crura of the diaphragm and the phreno-oesophageal ligament all play an important role in constricting the lower portion of the oesophagus and preventing reflux. Peristaltic movements do not stop the acid reflux.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      6.6
      Seconds
  • Question 27 - Cholesterol is synthesized in all of these organs EXCEPT? ...

    Correct

    • Cholesterol is synthesized in all of these organs EXCEPT?

      Your Answer: Stomach

      Explanation:

      The liver primarily synthesizes about 20-25% of the total daily cholesterol. Cholesterol is also synthesized to smaller extents in the adrenal glands, reproductive organs (as cholesterol is the precursor of sex hormones), skin and is also produced in the intestines.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      5.5
      Seconds
  • Question 28 - The transport of the di- and tri-peptides into enterocytes is by: ...

    Correct

    • The transport of the di- and tri-peptides into enterocytes is by:

      Your Answer: H+ dependent peptide transporter 1

      Explanation:

      Peptides longer that four amino acids are not absorbed. There is abundant absorption of di and tri peptidases in the small intestine. They are absorbed into the epithelial cell of the small intestine via a transporter called Peptide Transporter 1 by co transport with H+ ions.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.2
      Seconds
  • Question 29 - The lower oesophageal sphincter is under neural control. Which of the following causes...

    Incorrect

    • The lower oesophageal sphincter is under neural control. Which of the following causes contraction of the intrinsic sphincter?

      Your Answer: None of the above

      Correct Answer: Acetylcholine

      Explanation:

      The lower oesophageal sphincter (LOS) is a specific region of the oesophageal circular smooth muscle. It allows the passage of a food bolus to the stomach and prevents the reflux of gastric contents into the oesophagus. The tone of the LOS is myogenic in origin and depends on smooth muscle properties that lead to the opening of Ca2+ channels but can also be modulated by enteric motor neurons, the parasympathetic and sympathetic extrinsic nervous system and several neurohumoral substances. Nitric oxide causes LOS relaxation. Acetylcholine and tachykinins are involved in the LOS contraction.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      9.6
      Seconds
  • Question 30 - Which inhibitor of gastric enzyme secretion is released by the presence of fat...

    Incorrect

    • Which inhibitor of gastric enzyme secretion is released by the presence of fat in the jejunum?

      Your Answer: Acetylcholine

      Correct Answer: Peptide yy

      Explanation:

      Peptide yy is secreted from the jejunum due to the presence of fat. It inhibits gastric acid secretion and motility.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.4
      Seconds
  • Question 31 - Somatostatin is responsible for? ...

    Incorrect

    • Somatostatin is responsible for?

      Your Answer: Decreased fluid reabsorption

      Correct Answer: Decreased gastrin release

      Explanation:

      Somatostatin is an inhibitory hormone secreted from the D cells of the Pancreatic Islets. It causes the inhibition of gastrin (decreasing stomach acid production), CCK (decreasing gallbladder motility), gastrin inhibitory peptide and secretin. Gastrin production is also inhibited by secretin, GIP, VIP, glucagon and calcitonin.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.6
      Seconds
  • Question 32 - Where does most fat digestion begin? ...

    Incorrect

    • Where does most fat digestion begin?

      Your Answer: Stomach

      Correct Answer: Duodenum

      Explanation:

      Digestion of some fats can begin in the mouth where lingual lipase breaks down some short chain lipids into diglycerides. However fats are mainly digested in the small intestine (in the duodenum). The presence of fat in the small intestine produces hormones that stimulate the release of pancreatic lipase from the pancreas and bile from the liver which helps in the emulsification of fats for absorption of fatty acids.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.7
      Seconds
  • Question 33 - Peristalsis is an example of: ...

    Incorrect

    • Peristalsis is an example of:

      Your Answer: None of the options

      Correct Answer: Enteric nervous system

      Explanation:

      Peristalsis is a type of contraction where radial symmetrical contraction and relaxation of muscles propagates food in a downward wave through the gut. The enteric nervous system is one of the main divisions of the nervous system and consists of a mesh-like system of neurons that controls the function of the gastrointestinal tract. It has an independent reflex activity. The neurons of this system re collected into two types of ganglia: myenteric (or Auerbach’s) and submucosal (or Meissner’s plexuses). Myenteric plexuses are located between the inner and outer layers of the muscularis externa, while submucosal plexuses are located in the submucosa.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4
      Seconds
  • Question 34 - Which of the following is a product of D cells ...

    Incorrect

    • Which of the following is a product of D cells

      Your Answer: Gastrin releasing peptide (grp)

      Correct Answer: Somatostatin

      Explanation:

      Somatostatin is secreted by D cells, HCL and intrinsic factor secreted by parietal cells. Trefoil peptides are secreted by mucus secreting goblet cells and gastrin releasing peptide (grp) by post-ganglionic fibers of the vagus nerve (which innervate the G cells of the stomach).

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.3
      Seconds
  • Question 35 - Regarding carbohydrates absorption; ...

    Incorrect

    • Regarding carbohydrates absorption;

      Your Answer: Glucagon greatly decrease intestinal transport of sugars

      Correct Answer: Intestinal absorption of sugars is inhibited by the drug phlorizin

      Explanation:

      The main role of insulin is in the uptake of glucose from blood to tissues where it is metabolised. Glycose transporters in the intestines do not depend on the action of insulin. Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with glucose for the binding site, reducing intestinal and renal glucose transport.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.4
      Seconds
  • Question 36 - One function of the liver is synthesis and storage of protein. Which of...

    Correct

    • One function of the liver is synthesis and storage of protein. Which of the following will result in hypoalbuminemia?

      Your Answer: All of the above

      Explanation:

      Both trauma and sepsis cause an acute inflammatory response causing plasma leakage of albumin. Nephropathy causes leakage of albumin from glomeruli and excretion of albumin in urine known as albuminuria. A hypercatabolic state is characterized by increased circulating catabolic hormones and increase break down of proteins.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.4
      Seconds
  • Question 37 - The oligosaccharidases responsible for further digestion of starch after breakdown by the above...

    Incorrect

    • The oligosaccharidases responsible for further digestion of starch after breakdown by the above mentioned enzymes is located where?

      Your Answer: Salivary glands and fluids

      Correct Answer: Brush border of small intestine

      Explanation:

      The final step in digestion of carbohydrates, which is conversion of disaccharides to absorbable monosaccharides occurs on the small intestinal epithelial cells. The enzymes responsible for this final stage of digestion are not freely found in the intestinal lumen, but they are found as integral membrane proteins in the plasma membrane of the epithelial cell. The apical plasma membrane of the intestinal epithelial cell has numerous microvilli known as the brush border. Thus, the enzymes embedded in those microvilli are referred to as brush border enzymes.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.6
      Seconds
  • Question 38 - HCL is secreted by which cells in the stomach ...

    Correct

    • HCL is secreted by which cells in the stomach

      Your Answer: Parietal cells

      Explanation:

      Parietal cells are the epithelial cells that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and in the body of the stomach.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      11.1
      Seconds
  • Question 39 - In the gastric mucosa, which of the following cells is known to secrete...

    Incorrect

    • In the gastric mucosa, which of the following cells is known to secrete gastric lipase?

      Your Answer: Stem cell

      Correct Answer: Chief cell

      Explanation:

      Chief cells produce pepsinogen and gastric lipase. Parietal cells produce stomach acid and intrinsic factor.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.3
      Seconds
  • Question 40 - The chief cells of the stomach secrete which of the following? ...

    Incorrect

    • The chief cells of the stomach secrete which of the following?

      Your Answer: Intrinsic factor

      Correct Answer: Pepsinogens

      Explanation:

      A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a type of cell in the stomach that releases pepsinogen and gastric lipase.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      3.3
      Seconds
  • Question 41 - Which of the following would provide relief from nausea and vomiting? ...

    Incorrect

    • Which of the following would provide relief from nausea and vomiting?

      Your Answer: Bromocriptine

      Correct Answer: Cannabinoids

      Explanation:

      Ondansetron, chlorpromazine and haloperidol are effective antiemetic agents. Corticosteroids, cannabinoids, and benzodiazepines, alone or in combination with 5-HT3 and D2 antagonists, are also useful in the treatment of vomiting produced by chemotherapy.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.3
      Seconds
  • Question 42 - The infoldings or spaces between the bases of the villi are known as...

    Incorrect

    • The infoldings or spaces between the bases of the villi are known as

      Your Answer: Crypts of Brunner

      Correct Answer: Crypts of Lieberkühn

      Explanation:

      An intestinal gland (also crypt of Lieberkühn and intestinal crypt) is a gland found in the intestinal epithelium lining of the small intestine and large intestine (colon) between the villi.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.5
      Seconds
  • Question 43 - The lamina propria contains all of the following except: ...

    Incorrect

    • The lamina propria contains all of the following except:

      Your Answer: Plasma cells

      Correct Answer: Neutrophils

      Explanation:

      The connective tissue of the lamina propria is very loose, allowing it to be very cell rich. The cell population of the lamina propria is variable and can include, for example, fibroblasts, lymphocytes, plasma cells, macrophages, eosinophilic leukocytes, and mast cells. It provides support and nutrition to the epithelium, as well as the means to bind to the underlying tissue.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.9
      Seconds
  • Question 44 - The central veins in the liver: ...

    Incorrect

    • The central veins in the liver:

      Your Answer: Only the branches of portal vein coalesce to form the central vein

      Correct Answer: Coalesce to form the hepatic vein

      Explanation:

      The central veins coalesce to form the hepatic vein which in turn drains into the inferior vena cava. The portal vein mainly carries blood from different parts of the GIT and is not drained to the inferior vena cava.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.9
      Seconds
  • Question 45 - The intestine is lined by: ...

    Correct

    • The intestine is lined by:

      Your Answer: Simple columnar epithelium

      Explanation:

      In the small intestine, epithelium is simple columnar and specialised for absorption. The epithelium is arranged into villi, creating a brush border and increasing the area for absorption. The epithelium is simple columnar with microvilli.In the colon, epithelium is simple columnar and without villi. Goblet cells, which secrete mucous, are also present.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      2.8
      Seconds
  • Question 46 - The hepatic portal vein: ...

    Correct

    • The hepatic portal vein:

      Your Answer: Carries mainly nutrients from the GIT.

      Explanation:

      The portal vein contains oxygen as any other vein in the body does. The hepatic veins are responsible for venous drainage of the liver. The main function of the portal vein is to carry absorbed nutrients in the gut for metabolism and detoxification.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      5.2
      Seconds
  • Question 47 - Where in the gastrointestinal tract are valvulae conniventes? ...

    Incorrect

    • Where in the gastrointestinal tract are valvulae conniventes?

      Your Answer: Stomach

      Correct Answer: Jejunum

      Explanation:

      The circular folds (valves of Kerckring or valvulae conniventes) are large valvular flaps projecting into the lumen of the small intestine.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      4.2
      Seconds
  • Question 48 - Bile contains: ...

    Incorrect

    • Bile contains:

      Your Answer: Gastric juices, biliverdin, urea

      Correct Answer: Bile acids, phosphatidylcholine, cholesterol

      Explanation:

      The main components of bile include bile acids or bile salts, phospholipids; mainly phosphatidylcholine, cholesterol, bilirubin, inorganic salts; potassium, sodium and bicarbonate.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.7
      Seconds
  • Question 49 - Cholinergic neurons that pass into a retrograde direction activate neurons that release: ...

    Incorrect

    • Cholinergic neurons that pass into a retrograde direction activate neurons that release:

      Your Answer: Serotonin

      Correct Answer: Substance P and acetyl choline

      Explanation:

      Serotonin activates sensory neurons that activate the myenteric plexus. Cholinergic neurons passing in a retrograde direction in the myenteric plexus activate neurons that release substance P and acetylcholine, causing smooth muscle contraction.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      7.5
      Seconds
  • Question 50 - The blood supply to the greater curvature of the stomach is via the:...

    Incorrect

    • The blood supply to the greater curvature of the stomach is via the:

      Your Answer:

      Correct Answer: Right and left gastro-epiploic arteries

      Explanation:

      The blood supply to the greater curvature of the stomach is via the left and the right gastro-epiploic arteries branching from the splenic artery near the hilum.

    • This question is part of the following fields:

      • Gastrointestinal
      • Medicine
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Gastrointestinal (38/49) 78%
Medicine (38/49) 78%
Passmed