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  • Question 1 - Macrophages are derived from what type of white blood cell? ...

    Correct

    • Macrophages are derived from what type of white blood cell?

      Your Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      9.3
      Seconds

  • Question 2 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      When considering immunoglobulins in neonates. There are only a few key points you are likely to be tested on. 1. IgA is resistant to stomach acid and found in large amounts in breast milk. 2. IgG is the only Ig that can cross the placenta so is key for passive neonatal immunity 3. When the neonate starts synthesising its own Ig it is IgM that is produced first.

    • This question is part of the following fields:

      • Immunology
      8.3
      Seconds

  • Question 3 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Incorrect

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer: Type II

      Correct Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      10.2
      Seconds

  • Question 4 - Which of the following is a tumour marker for ovarian cancer? ...

    Correct

    • Which of the following is a tumour marker for ovarian cancer?

      Your Answer: Ca 125

      Explanation:

      CA-125 is the tumour marker specific for ovarian carcinoma.

    • This question is part of the following fields:

      • Immunology
      5.9
      Seconds

  • Question 5 - Which immunoglobulin provides passive immunity to the neonate? ...

    Correct

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      4.3
      Seconds

  • Question 6 - Which immunoglobulin is the first to be synthesised by the neonate? ...

    Correct

    • Which immunoglobulin is the first to be synthesised by the neonate?

      Your Answer: IgM

      Explanation:

      Fetal production of immunoglobulin begins early on at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth, through breast milk.

    • This question is part of the following fields:

      • Immunology
      5.7
      Seconds

  • Question 7 - Which of the following increases in pregnancy? ...

    Incorrect

    • Which of the following increases in pregnancy?

      Your Answer: IL-2

      Correct Answer: Th2

      Explanation:

      T-Helper cells type 2 increase during pregnancy. They secret cytokines IL-4,5,9,10 and 13.

    • This question is part of the following fields:

      • Immunology
      8.9
      Seconds

  • Question 8 - Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction? ...

    Incorrect

    • Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction?

      Your Answer: Type V

      Correct Answer: Type II

      Explanation:

      It is classified under type II hypersensitivity reaction. Antibodies are formed against the rhesus antigen i.e. D antigen. Hence when the Antibody reacts with the antigen on the RBC it results in activation of the complement cascade leading to lysis.

    • This question is part of the following fields:

      • Immunology
      6.9
      Seconds

  • Question 9 - Which of the following cell types act as professional antigen presenter cells (APCs)...

    Incorrect

    • Which of the following cell types act as professional antigen presenter cells (APCs)

      Your Answer: Interferon

      Correct Answer: Macrophages

      Explanation:

      Macrophages are the antigen presenting cells, they phagocytose the pathogen and after breaking them down present their protein structure to the B and T cells for a specific immune reaction to take place.

    • This question is part of the following fields:

      • Immunology
      14
      Seconds

  • Question 10 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      The major constituents of breast milk are lactose, protein, fat and water. However, the composition of breast milk is not constant; early lactation differs from late lactation, one feed differs from the next, and the composition can even change
      during a feed. Artificial infant formulas cannot therefore be identical to breast milk. In addition to IgA, breast milk contains small amounts of IgM and IgG and other factors such as lactoferrin, macrophages, complement and lysozymes

    • This question is part of the following fields:

      • Immunology
      5.2
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (6/10) 60%
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