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  • Question 1 - The role of the hemidesmosome is? ...

    Correct

    • The role of the hemidesmosome is?

      Your Answer: Attaches cells to underlying basal lamina

      Explanation:

      Hemidesmosomes connect the basal surface of epithelial cells via intermediate filaments to the underlying basal lamina. The transmembrane proteins of hemidesmosomes are not cadherins, but another type of protein called integrin.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      3.7
      Seconds

  • Question 2 - The formation of superoxide is catalysed by which enzyme? ...

    Correct

    • The formation of superoxide is catalysed by which enzyme?

      Your Answer: NADPH oxidase

      Explanation:

      Superoxide is biologically toxic and is deployed by the immune system to kill invading microorganisms. In phagocytes, superoxide is produced in large quantities by the enzyme NADPH oxidase for use in oxygen-dependent killing mechanisms of invading pathogens.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      26.1
      Seconds

  • Question 3 - The processing of NH3 to urea occurs in: ...

    Correct

    • The processing of NH3 to urea occurs in:

      Your Answer: Mitochondria and cytoplasm

      Explanation:

      The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea ((NH2)2CO) from ammonia (NH3). The urea cycle consists of four enzymatic reactions: one mitochondrial and three cytosolic.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      11.8
      Seconds

  • Question 4 - Which one of the following transporters is involved in facilitated diffusion? ...

    Correct

    • Which one of the following transporters is involved in facilitated diffusion?

      Your Answer: GLUT2

      Explanation:

      GLUT 2 is a bidirectional transporter, allowing glucose to flow in 2 directions via facilitated diffusion. Is expressed by renal tubular cells, liver cells and pancreatic beta cells. It is also present in the basolateral membrane of the small intestine epithelium.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      12.6
      Seconds

  • Question 5 - Microtubule subunits include: ...

    Correct

    • Microtubule subunits include:

      Your Answer: Alpha and beta tubulin

      Explanation:

      Microtubules are long, hollow cylinders made up of polymerised α- and β-tubulin dimers.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      4.5
      Seconds

  • Question 6 - Hydroxyl radicals are broken down by which of the following substance? ...

    Incorrect

    • Hydroxyl radicals are broken down by which of the following substance?

      Your Answer: Hydroxyl dismutase

      Correct Answer: Antioxidants

      Explanation:

      Unlike superoxide, which can be detoxified by superoxide dismutase, the hydroxyl radical cannot be eliminated by an enzymatic reaction but it is believed can be counteracted by antioxidants.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      12.8
      Seconds

  • Question 7 - Selectins ...

    Incorrect

    • Selectins

      Your Answer: Interact with protein ligands on immunoglobulins

      Correct Answer: Interact with carbohydrate ligands or mucin complexes on leucocytes and endothelial cells

      Explanation:

      Selectins are involved in constitutive lymphocyte homing, and in chronic and acute inflammation processes, including post-ischemic inflammation. Each selectin has a carbohydrate recognition domain that mediates binding to specific glycans on apposing cells.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      59.7
      Seconds

  • Question 8 - Cyclic AMP is broken down by which enzyme ...

    Correct

    • Cyclic AMP is broken down by which enzyme

      Your Answer: Phosphodiesterase

      Explanation:

      cAMP decomposition into AMP is catalysed by the enzyme phosphodiesterase.

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      5.3
      Seconds

  • Question 9 - In blistering dermatological disorders e.g.. Pemphigus, which junctions are attacked by autoantibodies? ...

    Correct

    • In blistering dermatological disorders e.g.. Pemphigus, which junctions are attacked by autoantibodies?

      Your Answer: Desmosomes

      Explanation:

      Pemphigus is an autoimmune disease caused by antibodies directed against both desmoglein 1 and desmoglein 3 present in desmosomes. Loss of desmosomes results in loss of cohesion between keratinocytes in the epidermis, and a disruption of the barrier function served by intact skin. The process is classified as a type II hypersensitivity reaction

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      20.8
      Seconds

  • Question 10 - Which intercellular connections are responsible for fastening the cells to one another? ...

    Correct

    • Which intercellular connections are responsible for fastening the cells to one another?

      Your Answer: Hemidesmosomes, zonula adherens & desmosomes

      Explanation:

      There are three major types of cell junction:Adherens junctions, desmosomes and hemidesmosomes (anchoring junctions),Gap junctions (communicating junction) &Tight junctions (occluding junctions)

    • This question is part of the following fields:

      • Cell Biology
      • Medicine
      47.3
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Cell Biology (8/10) 80%
Medicine (8/10) 80%
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