FCEM2-0991

FCEM2-0991

A 25-year-old woman is brought into the Emergency Department by the Security Guards. She is restrained and has scratched one of the Security Guards accompanying her. She is highly agitated and combative and has a history of bipolar disorder. She is given an initial dose of intramuscular olanzapine combined with intramuscular lorazepam. However, she shows no response and remains highly agitated and combative.

According to the NICE guidelines for short-term management of highly agitated and combative patients, which of the following drugs should be used next?