FCEM2-0733

A 48-year-old male presents to the emergency department complaining of abdominal pain and noticeable abdominal distension. Upon examination, you discover that the patient has a longstanding history of alcohol abuse. After conducting a thorough clinical assessment, you diagnose the patient with significant ascites, most likely caused by alcoholic liver disease. In terms of liver damage resulting from alcohol abuse, which of the following enzymes is primarily responsible for the oxidative metabolism of alcohol (ethanol) in the liver?